{"id":13852,"date":"2025-07-01T00:54:16","date_gmt":"2025-07-01T00:54:16","guid":{"rendered":"https:\/\/www.hnjournal.net\/?page_id=13852"},"modified":"2025-07-01T00:54:18","modified_gmt":"2025-07-01T00:54:18","slug":"6-7-4","status":"publish","type":"page","link":"https:\/\/www.hnjournal.net\/en\/6-7-4\/","title":{"rendered":""},"content":{"rendered":"<div class=\"journal-article\" style=\"margin-bottom: 20px;\"><h3 style='text-align: left; font-family:Times New Roman;'>Estimation of Vitamin D, B12, Zinc, and Ferritin in Women Have Hair-Loss<\/h3><h4 style='text-align: right; font-family:Simplified Arabic;'>\u062a\u0642\u062f\u064a\u0631 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0641\u064a\u062a\u0627\u0645\u064a\u0646 \u062f\u060c \u062812\u060c \u0627\u0644\u0632\u0646\u0643\u060c \u0648\u0627\u0644\u0641\u064a\u0631\u064a\u062a\u064a\u0646 \u0644\u062f\u0649 \u0627\u0644\u0646\u0633\u0627\u0621 \u0627\u0644\u0644\u0627\u062a\u064a \u064a\u0639\u0627\u0646\u064a\u0646 \u0645\u0646 \u062a\u0633\u0627\u0642\u0637 \u0627\u0644\u0634\u0639\u0631<\/h4><p style='text-align: left; font-weight:bold;'>Ghadeer Hamid AL- Ardhi<sup>1<\/sup><\/p><div style='direction: ltr; text-align: left; font-size:12px; line-height:1.5;'><p><sup>1<\/sup> DNA research Center, University of Babylon, Babylon,Hillah, Iraq.<\/p><p>Email: Ghadeer.hamid@uobabylon.edu.iq<\/p><\/div><p style='text-align:left;'><strong>DOI:<\/strong> <a href='https:\/\/doi.org\/https:\/\/doi.org\/10.53796\/hnsj67\/4' target='_blank' rel='noopener'>https:\/\/doi.org\/10.53796\/hnsj67\/4<\/a><\/p><p style='text-align: left;'><strong>Arabic Scientific Research Identifier:<\/strong> <a href='https:\/\/arsri.org\/10000\/67\/4' target='_blank' rel='noopener'>https:\/\/arsri.org\/10000\/67\/4<\/a><\/p><p style='text-align: left;'><strong>Volume (6) Issue (7). Pages:<\/strong> 42 - 46<\/p><p style='text-align: left;'><strong>Received at:<\/strong> 2025-06-07 | <strong>Accepted at:<\/strong> 2025-06-15 | <strong>Published at:<\/strong> 2025-07-01<\/p><p><a href='\/volume6\/issue7\/6-7-4.pdf' target='_blank' rel='noopener' style='background-color:green;color:white;padding:10px 15px;text-decoration:none;border-radius:5px;'>Download PDF<\/a><\/p>\r\n<style>\r\n.hnsj-cite-btn{\r\n  display:inline-flex; gap:8px; align-items:center;\r\n  padding:10px 14px; border-radius:10px;\r\n  border:1px solid #0b5ed7; background:#0b5ed7; color:#fff;\r\n  cursor:pointer; font-weight:700;\r\n}\r\n.hnsj-cite-btn:hover{background:#084bb0;border-color:#084bb0}\r\n.hnsj-cite-note{display:block;margin-top:6px;font-size:13px;opacity:.85}\r\n\r\n.hnsj-modal-backdrop{\r\n  position:fixed; inset:0; background:rgba(0,0,0,.55);\r\n  display:none; z-index:99998;\r\n}\r\n.hnsj-modal{\r\n  position:fixed; left:50%; top:50%; transform:translate(-50%,-50%);\r\n  width:min(760px,94vw); background:#fff; border-radius:14px;\r\n  box-shadow:0 12px 35px rgba(0,0,0,.28);\r\n  display:none; z-index:99999; overflow:hidden;\r\n  border:1px solid rgba(0,0,0,.08);\r\n}\r\n\r\n.hnsj-modal-header{\r\n  display:flex; justify-content:space-between; align-items:center;\r\n  padding:14px 16px; border-bottom:1px solid #eee; background:#f8fafc;\r\n}\r\n.hnsj-modal-title{font-size:16px;font-weight:800;color:#111827}\r\n.hnsj-modal-close{\r\n  border:1px solid #d1d5db; background:#fff;\r\n  width:34px; height:34px; border-radius:10px;\r\n  font-size:18px; cursor:pointer; line-height:0; color:#111827;\r\n}\r\n.hnsj-modal-close:hover{background:#f3f4f6}\r\n\r\n.hnsj-tabs{\r\n  display:flex; gap:10px; padding:10px 16px;\r\n  border-bottom:1px solid #f0f0f0; justify-content:flex-end;\r\n}\r\n.hnsj-tab{\r\n  padding:10px 14px; border-radius:10px;\r\n  border:1px solid #cfcfcf; background:#f3f4f6;\r\n  cursor:pointer; font-weight:800; color:#111827;\r\n}\r\n.hnsj-tab:hover{background:#e5e7eb;border-color:#9ca3af}\r\n.hnsj-tab.active{\r\n  background:#0b5ed7; border-color:#0b5ed7; color:#fff;\r\n  box-shadow:0 2px 10px rgba(11,94,215,.18);\r\n}\r\n\r\n.hnsj-modal-body{padding:14px 16px}\r\n.hnsj-row{\r\n  display:flex; gap:10px; flex-wrap:wrap; align-items:center;\r\n  margin-bottom:10px; justify-content:flex-end;\r\n}\r\n.hnsj-select{\r\n  padding:10px 12px; border-radius:10px;\r\n  border:1px solid #cfcfcf; min-width:220px;\r\n  background:#fff; color:#111827; font-weight:700;\r\n}\r\n.hnsj-copy{\r\n  padding:10px 14px; border-radius:10px;\r\n  border:1px solid #0b5ed7; background:#0b5ed7; color:#fff;\r\n  cursor:pointer; font-weight:800;\r\n}\r\n.hnsj-copy:hover{background:#084bb0;border-color:#084bb0}\r\n\r\n.hnsj-textarea{\r\n  width:100%; min-height:130px; padding:12px;\r\n  border-radius:12px; border:1px solid #cfcfcf;\r\n  line-height:1.7; resize:vertical; color:#111827; background:#fff;\r\n}\r\n.hnsj-actions{display:flex; justify-content:space-between; align-items:center; margin-top:10px; gap:10px; flex-wrap:wrap;}\r\n.hnsj-dl{\r\n  padding:10px 14px;\r\n  border-radius:10px;\r\n  border:1px solid #0b5ed7;\r\n  background:#0b5ed7;\r\n  color:#fff;\r\n  cursor:pointer;\r\n  font-weight:800;\r\n}\r\n.hnsj-dl:hover{background:#084bb0;border-color:#084bb0}\r\n\/* Force the citation modal UI to be independent from site RTL\/LTR *\/\r\n.hnsj-modal,\r\n.hnsj-modal *{\r\n  direction: ltr;\r\n  text-align: left;\r\n}\r\n\r\n\/* Keep the header title readable *\/\r\n.hnsj-modal-header{\r\n  direction: ltr;\r\n}\r\n<\/style>\r\n\r\n<script>\r\n(function(){\r\n  function slugifyFileName(s){\r\n    return (s || 'citation')\r\n      .toString()\r\n      .trim()\r\n      .replace(\/^https?:\\\/\\\/\/i,'')\r\n      .replace(\/[^a-z0-9]+\/gi,'-')\r\n      .replace(\/-+\/g,'-')\r\n      .replace(\/^-|-$\/g,'')\r\n      .toLowerCase();\r\n  }\r\n\r\n  function downloadTextFile(filename, content, mime){\r\n    var blob = new Blob([content], { type: mime || 'text\/plain;charset=utf-8' });\r\n    var url = URL.createObjectURL(blob);\r\n    var a = document.createElement('a');\r\n    a.href = url;\r\n    a.download = filename;\r\n    document.body.appendChild(a);\r\n    a.click();\r\n    a.remove();\r\n    setTimeout(function(){ URL.revokeObjectURL(url); }, 500);\r\n  }\r\n\r\n  function splitAuthors(str){\r\n    if(!str) return [];\r\n    return str\r\n      .split(\/,|\u061b|\u060c|;|\\n\/g)\r\n      .map(s => s.trim())\r\n      .filter(Boolean);\r\n  }\r\n\r\n  function buildRIS(m, langKey){\r\n    const title   = (langKey === 'ar') ? 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H. (2025). Estimation of Vitamin D, B12, Zinc, and Ferritin in Women Have Hair-Loss. Humanities &amp; Natural Sciences Journal, 6(7). https:\\\/\\\/doi.org\\\/10.53796\\\/hnsj67\\\/4&quot;,&quot;Chicago&quot;:&quot;Al-Ardhi Ghadeer Hamid. 2025. \\&quot;Estimation of Vitamin D, B12, Zinc, and Ferritin in Women Have Hair-Loss.\\&quot; Humanities &amp; Natural Sciences Journal 6, no. 7. https:\\\/\\\/doi.org\\\/10.53796\\\/hnsj67\\\/4&quot;,&quot;Harvard&quot;:&quot;Al-Ardhi G. H. 2025. Estimation of Vitamin D, B12, Zinc, and Ferritin in Women Have Hair-Loss. Humanities &amp; Natural Sciences Journal. [Internet] 2025-07-01. [Cited 2026-04-24]. 6(7). Available at: https:\\\/\\\/www.hnjournal.net\\\/6-7-4\\\/. https:\\\/\\\/doi.org\\\/10.53796\\\/hnsj67\\\/4&quot;,&quot;Vancouver&quot;:&quot;Al-Ardhi G. H. Estimation of Vitamin D, B12, Zinc, and Ferritin in Women Have Hair-Loss. Humanities &amp; Natural Sciences Journal. [Internet]. 2025-07-01; 6(7). Available from: https:\\\/\\\/doi.org\\\/10.53796\\\/hnsj67\\\/4&quot;,&quot;IEEE&quot;:&quot;Al-Ardhi G. H, \\&quot;Estimation of Vitamin D, B12, Zinc, and Ferritin in Women Have Hair-Loss,\\&quot; Humanities &amp; Natural Sciences Journal, vol. 6, no. 7, 2025. https:\\\/\\\/doi.org\\\/10.53796\\\/hnsj67\\\/4&quot;,&quot;MLA&quot;:&quot;Al-Ardhi Ghadeer Hamid. \\&quot;Estimation of Vitamin D, B12, Zinc, and Ferritin in Women Have Hair-Loss.\\&quot; Humanities &amp; Natural Sciences Journal, vol. 6, no. 7, 2025-07-01, https:\\\/\\\/doi.org\\\/10.53796\\\/hnsj67\\\/4&quot;}' data-cit-ar='{&quot;APA&quot;:&quot;AL- Ardhi G. H. (2025). \u062a\u0642\u062f\u064a\u0631 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0641\u064a\u062a\u0627\u0645\u064a\u0646 \u062f\u060c \u062812\u060c \u0627\u0644\u0632\u0646\u0643\u060c \u0648\u0627\u0644\u0641\u064a\u0631\u064a\u062a\u064a\u0646 \u0644\u062f\u0649 \u0627\u0644\u0646\u0633\u0627\u0621 \u0627\u0644\u0644\u0627\u062a\u064a \u064a\u0639\u0627\u0646\u064a\u0646 \u0645\u0646 \u062a\u0633\u0627\u0642\u0637 \u0627\u0644\u0634\u0639\u0631. \u0645\u062c\u0644\u0629 \u0627\u0644\u0639\u0644\u0648\u0645 \u0627\u0644\u0627\u0646\u0633\u0627\u0646\u064a\u0629 \u0648\u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629\u060c 6(7). https:\\\/\\\/doi.org\\\/10.53796\\\/hnsj67\\\/4&quot;,&quot;Chicago&quot;:&quot;AL- Ardhi Ghadeer Hamid. 2025. \u00ab\u062a\u0642\u062f\u064a\u0631 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0641\u064a\u062a\u0627\u0645\u064a\u0646 \u062f\u060c \u062812\u060c \u0627\u0644\u0632\u0646\u0643\u060c \u0648\u0627\u0644\u0641\u064a\u0631\u064a\u062a\u064a\u0646 \u0644\u062f\u0649 \u0627\u0644\u0646\u0633\u0627\u0621 \u0627\u0644\u0644\u0627\u062a\u064a \u064a\u0639\u0627\u0646\u064a\u0646 \u0645\u0646 \u062a\u0633\u0627\u0642\u0637 \u0627\u0644\u0634\u0639\u0631\u00bb. \u0645\u062c\u0644\u0629 \u0627\u0644\u0639\u0644\u0648\u0645 \u0627\u0644\u0627\u0646\u0633\u0627\u0646\u064a\u0629 \u0648\u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629\u060c 6(7). https:\\\/\\\/doi.org\\\/10.53796\\\/hnsj67\\\/4&quot;,&quot;Harvard&quot;:&quot;AL- Ardhi G. H. \u062a\u0642\u062f\u064a\u0631 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0641\u064a\u062a\u0627\u0645\u064a\u0646 \u062f\u060c \u062812\u060c \u0627\u0644\u0632\u0646\u0643\u060c \u0648\u0627\u0644\u0641\u064a\u0631\u064a\u062a\u064a\u0646 \u0644\u062f\u0649 \u0627\u0644\u0646\u0633\u0627\u0621 \u0627\u0644\u0644\u0627\u062a\u064a \u064a\u0639\u0627\u0646\u064a\u0646 \u0645\u0646 \u062a\u0633\u0627\u0642\u0637 \u0627\u0644\u0634\u0639\u0631. \u0645\u062c\u0644\u0629 \u0627\u0644\u0639\u0644\u0648\u0645 \u0627\u0644\u0627\u0646\u0633\u0627\u0646\u064a\u0629 \u0648\u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629. [\u0627\u0646\u062a\u0631\u0646\u062a] 2025-07-01. [\u062a\u0627\u0631\u064a\u062e \u0627\u0644\u0648\u0635\u0648\u0644 2026-04-24]. 6(7). \u0645\u062a\u0627\u062d \u0639\u0644\u0649: https:\\\/\\\/www.hnjournal.net\\\/6-7-4\\\/. https:\\\/\\\/doi.org\\\/10.53796\\\/hnsj67\\\/4&quot;,&quot;Vancouver&quot;:&quot;AL- Ardhi G. H. \u062a\u0642\u062f\u064a\u0631 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0641\u064a\u062a\u0627\u0645\u064a\u0646 \u062f\u060c \u062812\u060c \u0627\u0644\u0632\u0646\u0643\u060c \u0648\u0627\u0644\u0641\u064a\u0631\u064a\u062a\u064a\u0646 \u0644\u062f\u0649 \u0627\u0644\u0646\u0633\u0627\u0621 \u0627\u0644\u0644\u0627\u062a\u064a \u064a\u0639\u0627\u0646\u064a\u0646 \u0645\u0646 \u062a\u0633\u0627\u0642\u0637 \u0627\u0644\u0634\u0639\u0631. \u0645\u062c\u0644\u0629 \u0627\u0644\u0639\u0644\u0648\u0645 \u0627\u0644\u0627\u0646\u0633\u0627\u0646\u064a\u0629 \u0648\u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629. [\u0627\u0646\u062a\u0631\u0646\u062a]. 2025-07-01\u061b 6(7). \u0645\u062a\u0627\u062d \u0645\u0646: https:\\\/\\\/doi.org\\\/10.53796\\\/hnsj67\\\/4&quot;,&quot;IEEE&quot;:&quot;AL- Ardhi G. H. \u00ab\u062a\u0642\u062f\u064a\u0631 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0641\u064a\u062a\u0627\u0645\u064a\u0646 \u062f\u060c \u062812\u060c \u0627\u0644\u0632\u0646\u0643\u060c \u0648\u0627\u0644\u0641\u064a\u0631\u064a\u062a\u064a\u0646 \u0644\u062f\u0649 \u0627\u0644\u0646\u0633\u0627\u0621 \u0627\u0644\u0644\u0627\u062a\u064a \u064a\u0639\u0627\u0646\u064a\u0646 \u0645\u0646 \u062a\u0633\u0627\u0642\u0637 \u0627\u0644\u0634\u0639\u0631\u00bb. \u0645\u062c\u0644\u0629 \u0627\u0644\u0639\u0644\u0648\u0645 \u0627\u0644\u0627\u0646\u0633\u0627\u0646\u064a\u0629 \u0648\u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629\u060c \u0645 6\u060c \u0639 7\u060c 2025. https:\\\/\\\/doi.org\\\/10.53796\\\/hnsj67\\\/4&quot;,&quot;MLA&quot;:&quot;AL- Ardhi Ghadeer Hamid. \u00ab\u062a\u0642\u062f\u064a\u0631 \u0645\u0633\u062a\u0648\u064a\u0627\u062a \u0641\u064a\u062a\u0627\u0645\u064a\u0646 \u062f\u060c \u062812\u060c \u0627\u0644\u0632\u0646\u0643\u060c \u0648\u0627\u0644\u0641\u064a\u0631\u064a\u062a\u064a\u0646 \u0644\u062f\u0649 \u0627\u0644\u0646\u0633\u0627\u0621 \u0627\u0644\u0644\u0627\u062a\u064a \u064a\u0639\u0627\u0646\u064a\u0646 \u0645\u0646 \u062a\u0633\u0627\u0642\u0637 \u0627\u0644\u0634\u0639\u0631\u00bb. \u0645\u062c\u0644\u0629 \u0627\u0644\u0639\u0644\u0648\u0645 \u0627\u0644\u0627\u0646\u0633\u0627\u0646\u064a\u0629 \u0648\u0627\u0644\u0637\u0628\u064a\u0639\u064a\u0629\u060c \u0645 6\u060c \u0639 7\u060c 2025-07-01\u060c https:\\\/\\\/doi.org\\\/10.53796\\\/hnsj67\\\/4&quot;}'>\r\n    <div class='hnsj-modal-header'>\r\n    <div class='hnsj-modal-title'>Cite \/ \u0627\u0644\u0627\u0633\u062a\u0634\u0647\u0627\u062f<\/div>\r\n    <button class='hnsj-modal-close' type='button' data-hnsj-close aria-label='Close'>\u00d7<\/button>\r\n    <\/div>\r\n\r\n    <div class='hnsj-tabs'>\r\n      <button type='button' class='hnsj-tab active' data-lang='en'>English (Roman)<\/button>\r\n      <button type='button' class='hnsj-tab' data-lang='ar'>\u0627\u0644\u0639\u0631\u0628\u064a\u0629<\/button>\r\n    <\/div>\r\n\r\n    <div class='hnsj-modal-body'>\r\n      <div class='hnsj-row'>\r\n        <button type='button' class='hnsj-copy' data-hnsj-copy>Copy<\/button>\r\n        <select class='hnsj-select' data-hnsj-style><\/select>\r\n        <\/div>\r\n\r\n      <textarea class='hnsj-textarea' data-hnsj-box readonly><\/textarea>\r\n\r\n      <div class='hnsj-actions'>\r\n        <div style='display:flex; gap:10px; flex-wrap:wrap;'>\r\n          <button type='button' class='hnsj-dl' data-hnsj-dl='ris'>Download RIS<\/button>\r\n          <button type='button' class='hnsj-dl' data-hnsj-dl='bib'>Download BibTeX<\/button>\r\n        <\/div>\r\n      <\/div>\r\n    <\/div>\r\n  <\/div>\r\n<\/div>\r\n<p style='text-align:justify; direction:ltr;'><strong>Abstract:<\/strong> Hair loss (Alopecia) is a common condition among women, defined as an abnormal loss of hair density, and may have multiple causes including genetics, hormonal, and psychological factors, as well as deficiencies in certain micronutrients. The objective of this study was to evaluate the levels of a number of essential nutrients associated with hair health, included: vitamin D, vitamin B12, ferritin, and zinc in women with hair loss compared to group of healthy women (control group). One handed and twenty (120) women them age around (20-45) years were collected, (90 women) with hair loss and (30 women) as a control group. ELISA kit was used to measure vitamins and elements levels in serum of blood. The findings of the study indicated a significant decline in vitamin D and ferritin levels in affected women compared to control subjects((p\u22640.05)). Statistically positive correlations was detected between vitamin D and ferritin, and between vitamin D and vitamin B12, and between zinc and vitamin B12. These findings indicate the interaction between these elements and their potential role they play in the possibility of hair loss, which confirms the importance of an integrated nutritional assessment in these cases, indicating a potential role of these micronutrient in regulating scalp health and hair growth.<\/p><p style='text-align:left; direction:ltr;'><strong>Keywords: <\/strong> vitamin D3, Zink, B12, Ferritin, Hair-loss.<\/p><p style='text-align:justify; direction:rtl;'><strong>\u0627\u0644\u0645\u0633\u062a\u062e\u0644\u0635: <\/strong> \u062a\u0633\u0627\u0642\u0637 \u0627\u0644\u0634\u0639\u0631 (\u0627\u0644\u062b\u0639\u0644\u0628\u0629) \u0647\u0648 \u062d\u0627\u0644\u0629 \u0634\u0627\u0626\u0639\u0629 \u0628\u064a\u0646 \u0627\u0644\u0646\u0633\u0627\u0621\u060c \u0648\u064a\u0639\u0631\u0641 \u0628\u0641\u0642\u062f\u0627\u0646 \u063a\u064a\u0631 \u0637\u0628\u064a\u0639\u064a \u0641\u064a \u0643\u062b\u0627\u0641\u0629 \u0627\u0644\u0634\u0639\u0631\u060c 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\u0627\u0644\u0646\u062a\u0627\u0626\u062c \u0625\u0644\u0649 \u0627\u0644\u062a\u0641\u0627\u0639\u0644 \u0628\u064a\u0646 \u0647\u0630\u0647 \u0627\u0644\u0639\u0646\u0627\u0635\u0631 \u0648\u0627\u0644\u062f\u0648\u0631 \u0627\u0644\u0645\u062d\u062a\u0645\u0644 \u0627\u0644\u0630\u064a \u062a\u0644\u0639\u0628\u0647 \u0641\u064a \u0625\u0645\u0643\u0627\u0646\u064a\u0629 \u062a\u0633\u0627\u0642\u0637 \u0627\u0644\u0634\u0639\u0631\u060c \u0645\u0645\u0627 \u064a\u0624\u0643\u062f \u0623\u0647\u0645\u064a\u0629 \u0627\u0644\u062a\u0642\u064a\u064a\u0645 \u0627\u0644\u063a\u0630\u0627\u0626\u064a \u0627\u0644\u0645\u062a\u0643\u0627\u0645\u0644 \u0641\u064a \u0647\u0630\u0647 \u0627\u0644\u062d\u0627\u0644\u0627\u062a\u060c \u0645\u0634\u064a\u0631\u064b\u0627 \u0625\u0644\u0649 \u062f\u0648\u0631 \u0645\u062d\u062a\u0645\u0644 \u0644\u0647\u0630\u0647 \u0627\u0644\u0645\u063a\u0630\u064a\u0627\u062a \u0627\u0644\u062f\u0642\u064a\u0642\u0629 \u0641\u064a \u062a\u0646\u0638\u064a\u0645 \u0635\u062d\u0629 \u0641\u0631\u0648\u0629 \u0627\u0644\u0631\u0623\u0633 \u0648\u0646\u0645\u0648 \u0627\u0644\u0634\u0639\u0631.<\/p><p style='text-align:right;'><strong>\u0627\u0644\u0643\u0644\u0645\u0627\u062a \u0627\u0644\u0645\u0641\u062a\u0627\u062d\u064a\u0629: <\/strong> \u0641\u064a\u062a\u0627\u0645\u064a\u0646 \u062f3\u060c \u0627\u0644\u0632\u0646\u0643\u060c \u0641\u064a\u062a\u0627\u0645\u064a\u0646 \u062812\u060c \u0627\u0644\u0641\u064a\u0631\u064a\u062a\u064a\u0646\u060c \u062a\u0633\u0627\u0642\u0637 \u0627\u0644\u0634\u0639\u0631.<\/p><\/div>\n\n\n<p dir=\"ltr\" style=\"text-align: justify;\"><strong>Introduction<\/strong><\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\">Hair-loss is a prevalent case that influences a high ratio of women of all ages, and its causes variable based on multi factors such as; genetics, hormonal, psychological, and nutritional factors (1). Studies have shown that deficiencies in certain micronutrients play an important role in disrupting the hair growth cycle, causing an increased rate of hair loss (2,3). Vitamin D, zinc, ferritin, and vitamin B12 have be given a special attention due to their vital physiological role in maintaining a healthy scalp and hair follicles (4).<\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\">Vitamin D is a key regulator in the hair growth cycle through its effect on vitamin D receptors found in hair follicles, and its deficiency is thought to be related to various types of hair-loss as \u201calopecia areata\u201d so \u201calopecia\u201d(5). Zinc is an essential element implicated in cell division as well as protein production, and its deficiency can lead to brittle, weak, and easily lost hair (6).<\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\">On the other hand, ferritin, the stored form of iron, is an important indicator of iron status in the body, and low levels have been shown to be strongly associated with chronic hair-loss in women, even in the absence of overt anemia (7). Vitamin B12 is involved in metabolism, blood cell formation, and neurotransmitters, and it\u2019s thought that its deficiency may contribute to hair loss through its effect on scalp circulation and cell regeneration (8).<\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\">Objective of current research is to estimate the concentrations of these nutrients in female patients experiencing hair loss. The findings may elucidate the correlation between nutrient deficiencies and hair loss, thereby providing a foundation for treatment recommendations that are informed by meticulous nutritional assessments.<\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\"><strong>Material and Method<\/strong><\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\">The study comprised a sample of 120 women aged 20-45 years, who has been recruited from various dermatology clinics in the city of Al- Hilla, which is situated within the province of Babylon for this study, during the period from September 2024 to March 2025.<\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\">The samples divided into two groups: the first group (n=90): women with hair loss not caused by known skin diseases. The second group(n=30): control group, not suffering from hair loss.<\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\">Blood sample were collected from all participants to measure levels of vitamin D(25(OH)D), vitamin B12, ferritin, and zinc. Five milliliters of blood were obtained via venipuncture after an overnights fast between 8:30 a.m. and 11:30 a.m. Serum levels of Vitamin D<sub>3<\/sub> were measured using commercially available enzyme-linked-immunosorbent-assay(ELISA)kit \u201cPars-Biochem-Nanjing-Jiangsu-China\u201d in strict accordance with the \u201cmanufacturer\u2019s instructions<sup>\u201d<\/sup>.<\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\">Statistical analysis: The analyses were conducted utilizing [IBM,SPSS] statistics, version 23 (IBM-Armonk- New York-USA). T- test was used to compare means, and Pearson\u2019s correlation coefficient was used to examine relationship between variables.<\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\"><strong>Results<\/strong><\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\">The finding indicated a significant decline (p&lt;0.05) in the mean levels of vitamin D3(18.35\u00b10.68) and ferritin (71.04\u00b18.15) in affected women compared to the control group (31.26\u00b11.53), (142.80\u00b115.40) respectively.<\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\">That study found that there are unavailable statistically significant differences in vitamin B12 and zinc levels between the two groups, but relatively lower levels were recorded in the case group as showed in figure 1.<\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\"><strong>184.66 \u00b114.25 172.77\u00b16.29<\/strong><\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\"><strong>31.26\u00b11.53 18.35\u00b10.68 * <\/strong><\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\"><strong>Figure 1: Measured parameters {vitamin D, vitamin B12, zinc, and ferritin} in study group<\/strong><\/p>\n<ul dir=\"ltr\" style=\"text-align: justify;\">\n<li><strong>The values represent mean \u00b1 SE<\/strong><\/li>\n<li><strong>* statistically significant of patients VS normal subjects (p\u2264 0.05).<\/strong><\/li>\n<\/ul>\n<p dir=\"ltr\" style=\"text-align: justify;\">There was a significant positive correlation observed between: vitamin D and ferritin (r=0.195, p=0.03), vitamin D and vitamin B12 (r=0.173, p=0.04), so zinc and vitamin B12(r=0.50, p=0.00) as exhibit in table 1.<\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\"><strong>Table 1: Relationship between vitamin D, vitamin B12, zinc, and ferritin levels in Study Groups<\/strong><\/p>\n<table dir=\"ltr\">\n<tbody>\n<tr>\n<td>\n<p>Correlations<\/p>\n<\/td>\n<td colspan=\"2\">\n<p>Vitamin D3<\/p>\n<p>r p<\/p>\n<\/td>\n<td colspan=\"2\">\n<p>B12<\/p>\n<p>r p<\/p>\n<\/td>\n<td colspan=\"2\">\n<p>Zink<\/p>\n<p>r p<\/p>\n<\/td>\n<td colspan=\"2\">\n<p>Ferritin<\/p>\n<p>r p<\/p>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<p>Vitamin D3<\/p>\n<\/td>\n<td colspan=\"2\">\n<p><strong>1<\/strong><\/p>\n<\/td>\n<td>\n<p><strong>0.173*<\/strong><\/p>\n<\/td>\n<td>\n<p><strong>0.04<\/strong><\/p>\n<\/td>\n<td>\n<p><strong>0.02<\/strong><\/p>\n<\/td>\n<td>\n<p><strong>0.76<\/strong><\/p>\n<\/td>\n<td>\n<p><strong>0.195*<\/strong><\/p>\n<\/td>\n<td>\n<p><strong>0.03<\/strong><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<p>B12<\/p>\n<\/td>\n<td>\n<p><strong>0.173*<\/strong><\/p>\n<\/td>\n<td>\n<p><strong>0.05<\/strong><\/p>\n<\/td>\n<td colspan=\"2\">\n<p><strong>1<\/strong><\/p>\n<\/td>\n<td>\n<p><strong>0.50**<\/strong><\/p>\n<\/td>\n<td>\n<p><strong>0.00<\/strong><\/p>\n<\/td>\n<td>\n<p><strong>&#8211; 0.16<\/strong><\/p>\n<\/td>\n<td>\n<p><strong>0.08<\/strong><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<p>Zink<\/p>\n<\/td>\n<td>\n<p><strong>0.02<\/strong><\/p>\n<\/td>\n<td>\n<p><strong>0.76<\/strong><\/p>\n<\/td>\n<td>\n<p><strong>0.50**<\/strong><\/p>\n<\/td>\n<td>\n<p><strong>0.00<\/strong><\/p>\n<\/td>\n<td colspan=\"2\">\n<p><strong>1<\/strong><\/p>\n<\/td>\n<td>\n<p><strong>&#8211; 0.03<\/strong><\/p>\n<\/td>\n<td>\n<p><strong>0.68<\/strong><\/p>\n<\/td>\n<\/tr>\n<tr>\n<td>\n<p>Ferritin<\/p>\n<\/td>\n<td>\n<p><strong>0.195*<\/strong><\/p>\n<\/td>\n<td>\n<p><strong>0.03<\/strong><\/p>\n<\/td>\n<td>\n<p><strong>&#8211; 0.16<\/strong><\/p>\n<\/td>\n<td>\n<p><strong>0.08<\/strong><\/p>\n<\/td>\n<td>\n<p><strong>&#8211; 0.03<\/strong><\/p>\n<\/td>\n<td>\n<p><strong>0.68<\/strong><\/p>\n<\/td>\n<td colspan=\"2\">\n<p><strong>1<\/strong><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p dir=\"ltr\" style=\"text-align: justify;\"><strong>*sign statistical significant at 0.05., **sign statistical significant at 0.01.<\/strong><\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\"><strong>Discussion<\/strong><\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\">The discovered correlations between the studied elements also reflect the overlap of their biological functions, with vitamin D and vitamin B12 involved in cell proliferation, while zinc in several enzymatic reactions that affect hair growth.<\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\">The data indicate that vitamin D and ferritin deficiency is significantly associated with female hair-loss, which is compatible to previous studies indicating the role of vitamin D in regulating the hair follicle cycle and the role of ferritin as an indicator of iron stores, essential for hair follicle cell proliferation(9,10).<\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\">Recent studies indicate that there is a strong correlation between deficiency of certain vitamins and minerals and hair loss in women, especially in cases of chronic or patterned hair loss (11,12). The positive correlation of vitamin D3 and ferritin, this result corresponding with the study demonstrated that ferritin and vitamin Dlevels were significantly lower as comparison to the control subjects (13). These finding suggest that ferritin and vitaminD deficiency may have a contributory function in hair-loss in women, so patients should have their levels assessed and supplementation provided as needed.<\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\">The findings of correlation study indicated a positive correlation between vitamin D and vitaminB12, as well as ferritin. Some studies have proposed a relationship of vitaminD so both vitaminB12 and ferritin, Banihashemi <em>et al<\/em>, showed a subjects having loss of hair had a decline in concentration of vitamin D and ferritin than normal subjects (control) (14). However, there are not enough studies showing a direct relationship between vitamin D and vitamin B12, requiring further studies to investigate this condition.<\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\">The positive correlation of vitamin B12 and zinc in this study corresponding with study showed that a positive relationship between vitamin B12 and zinc levels, this finding suggest that zinc deficiency may affect vitamin B12 levels, warranting evaluation of the levels of both elements in patients with hair-loss or other symptoms associated with deficiency of these elements(15,16).<\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\"><strong>Conclusion<\/strong><\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\">The study found that female subjects experiencing hair loss exhibited significantly decline levels of vitamin D and ferritin in comparison to healthy subjects. there are clear correlations between the elements studied, highlighting the importance of an integrated nutritional assessment in cases of hair loss. Periodic assessment of vitamin and mineral levels in affected women and evidence based nutritional and therapeutic interventions are recommended.<\/p>\n<p dir=\"ltr\" style=\"text-align: justify;\"><strong>Recommendations<\/strong><\/p>\n<ol dir=\"ltr\" style=\"text-align: justify;\">\n<li><strong>Nutritional Supplementation<\/strong>: Regular supplementation of Vitamin D3 and ferritin for women with deficiencies should be considered as part of hair loss management.<\/li>\n<li><strong>Routine Nutritional Assessment<\/strong>: Routine evaluation of Vitamin D, B12, Zinc, and Ferritin levels should be incorporated into dermatology clinics for women experiencing hair loss.<\/li>\n<li><strong>Dietary Counseling<\/strong>: Advise women with hair loss to include nutrient-rich foods such as fatty fish, red meat, legumes, nuts, and fortified cereals.<\/li>\n<li><strong>Further Research on Vitamin D and B12<\/strong>: Investigate the interaction between Vitamin D and Vitamin B12 and their collective role in hair health.<\/li>\n<li><strong>Longitudinal Studies<\/strong>: Conduct longer-term studies to observe changes in nutrient levels and hair growth over time.<\/li>\n<li><strong>Psychological and Hormonal Assessments<\/strong>: Incorporate assessments for psychological and hormonal factors, as they can also influence hair loss.<\/li>\n<\/ol>\n<p dir=\"ltr\" style=\"text-align: justify;\"><strong>References<\/strong><\/p>\n<ol dir=\"ltr\" style=\"text-align: justify;\">\n<li>Gokce, N., Basgoz, N., Kenanoglu, S., Akalin, H., Ozkul, Y., Ergoren, M. C., &#8230; &amp; Dundar, M. (2022). An overview of the genetic aspects of hair loss and its connection with nutrition.\u00a0<em>Journal of preventive medicine and hygiene<\/em>,\u00a0<em>63<\/em>(2 Suppl 3), E228.<\/li>\n<li>Ruiz-Tagle, S. A., Figueira, M. M., Vial, V., Espinoza-Benavides, L., &amp; Miteva, M. (2018). Micronutrients in hair loss.\u00a0<em>Our Dermatology Online\/Nasza Dermatologia Online<\/em>,\u00a0<em>9<\/em>(3).<\/li>\n<li>Labrozzi, A. (2020). Nutrients in hair supplements: evaluation of their function in hair loss treatment.\u00a0<em>Hair Ther Transplant<\/em>,\u00a0<em>10<\/em>(1), 1-6.<\/li>\n<li>Yongpisarn, T., Tejapira, K., Thadanipon, K., &amp; Suchonwanit, P. (2024). Vitamin D deficiency in non-scarring and scarring alopecias: a systematic review and meta-analysis.\u00a0<em>Frontiers in Nutrition<\/em>,\u00a0<em>11<\/em>, 1479337.<\/li>\n<li>Rasheed, H., Mahgoub, D., Hegazy, R., El-Komy, M., Abdel Hay, R., Hamid, M. A., &amp; Hamdy, E. (2013). Serum ferritin and vitamin d in female hair loss: do they play a role?\u00a0<em>Skin pharmacology and physiology<\/em>,\u00a0<em>26<\/em>(2), 101-107.<\/li>\n<li>Durusu Turkoglu, I. N., Turkoglu, A. K., Soylu, S., Gencer, G., &amp; Duman, R. (2024). A comprehensive investigation of biochemical status in patients with telogen effluvium: Analysis of Hb, ferritin, vitamin B12, vitamin D, thyroid function tests, zinc, copper, biotin, and selenium levels.\u00a0<em>Journal of Cosmetic Dermatology<\/em>,\u00a0<em>23<\/em>(12), 4277-4284.<\/li>\n<li>Zhang, D., LaSenna, C., &amp; Shields, B. E. (2023). Serum ferritin levels: A clinical guide in patients with hair loss.\u00a0<em>Cutis<\/em>,\u00a0<em>112<\/em>(2), 62-67.<\/li>\n<li>Almohanna, H. M., Ahmed, A. A., Tsatalis, J. P., &amp; Tosti, A. (2019). The role of vitamins and minerals in hair loss: a review.\u00a0<em>Dermatology and therapy<\/em>,\u00a0<em>9<\/em>(1), 51-70.<\/li>\n<li>Falih, I. Q. (2023). The Effect of Ferritin, vitamin D, and some hormonal and biochemical parameters on patients with female-pattern hair loss after COVID-19 infection.\u00a0<em>Journal of Preventive, Diagnostic and Treatment Strategies in Medicine<\/em>,\u00a0<em>2<\/em>(4), 218-223.<\/li>\n<li>Al-makhzoomy, T. A. K., Kadhim, D. A., &amp; Ali, A. R. M. (2024). Assessment of Vitamin D and Correlation of It with Other Bio-chemical Parameters Related to Hair Loss.\u00a0<em>Healthcare Studies<\/em>,\u00a0<em>2<\/em>(2), 1-8.<\/li>\n<li>Mustafa, T. (2024). I. Evaluation of hair loss and some physiological factors in female\u2019s patiens attended dermatological clinics at Ramadi General Hospital.\u00a0<em>Central Asian Journal of Medical and Natural Science<\/em>,\u00a0<em>5<\/em>(4), 711-721.<\/li>\n<li>Tamer, F., Yuksel, M., &amp; Karabag, Y. (2020). Serum ferritin and vitamin D levels should be evaluated in patients with diffuse hair loss prior to treatment.\u00a0<em>Advances in Dermatology and Allergology\/Post\u0119py Dermatologii i Alergologii<\/em>,\u00a0<em>37<\/em>(3), 407-411.<\/li>\n<li>Ergul, A. B., Turanoglu, C., Karakukcu, C., Kazanci, E. G., &amp; Torun, Y. A. (2018). Increased vitamin B12 levels in children with zinc deficiency.\u00a0<em>International Journal for Vitamin and Nutrition Research<\/em>.<\/li>\n<li>Banihashemi, M., Nahidi, Y., Meibodi, N. T., Jarahi, L., &amp; Dolatkhah, M. (2016). Serum vitamin D3 level in patients with female pattern hair loss.\u00a0<em>International journal of trichology<\/em>,\u00a0<em>8<\/em>(3), 116-120.<\/li>\n<li>Mahdi, S. A. H., &amp; Mohammed, H. A. A. (2022). Effect of zinc, ferritin, and vitamin B12 deficiency on hair loss in pregnant women.\u00a0<em>International journal of health sciences<\/em>,\u00a0<em>6<\/em>(S4), 9737-9747.<\/li>\n<li>Salechaa, A. J., Sai-Sameer, A. V., Annamreddy, L., Siva-Priyanka, V. P., Kumar-AL, S., &amp; Rama-Murthy, D. V. S. B. (2024). A comparative study on the association of serum ferritin and vitamin D, and B12 levels among individuals with hair loss.\u00a0<em>Portuguese Journal of Dermatology &amp; Venereology<\/em>,\u00a0<em>82<\/em>(1).<\/li>\n<\/ol>\n<p dir=\"ltr\" style=\"text-align: justify;\">\u00a0<\/p>","protected":false},"excerpt":{"rendered":"<p>Introduction Hair-loss is a prevalent case that influences a high ratio of women of all ages, and its causes variable based on multi factors such as; genetics, hormonal, psychological, and [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"om_disable_all_campaigns":false,"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_joinchat":[],"footnotes":""},"class_list":["post-13852","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.hnjournal.net\/en\/wp-json\/wp\/v2\/pages\/13852","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.hnjournal.net\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.hnjournal.net\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.hnjournal.net\/en\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/www.hnjournal.net\/en\/wp-json\/wp\/v2\/comments?post=13852"}],"version-history":[{"count":1,"href":"https:\/\/www.hnjournal.net\/en\/wp-json\/wp\/v2\/pages\/13852\/revisions"}],"predecessor-version":[{"id":13856,"href":"https:\/\/www.hnjournal.net\/en\/wp-json\/wp\/v2\/pages\/13852\/revisions\/13856"}],"wp:attachment":[{"href":"https:\/\/www.hnjournal.net\/en\/wp-json\/wp\/v2\/media?parent=13852"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}